Small ubiquitin-related modifier 2

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August undefined, 2024

WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in … WebMay 2, 2024 · Small ubiquitin-related modifier (SUMO)–specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, …

SUMO2 Gene - GeneCards SUMO2 Protein SUMO2 Antibody

WebJul 22, 2014 · Small ubiquitin-related modifier (SUMO), one of these UBLs, is an essential PTM in eukaryotic cells that is involved in various cellular functions including gene expression regulation, DNA repair, intracellular transport, and response to viral and bacterial infections ( 1 – 5 ). WebSUMO (small ubiquitin-related modifier) proteins are ∼ 10-kD polypeptides that function as reversible post-translational protein modifiers. They form isopeptide bonds with ɛ-amino … can a uti cause confusion in older people

Small ubiquitin‐related modifiers: A novel and independent

WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase activity)andremovingconjugatedSUMOfromtargets(isopep … WebSmall ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family (1). The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to … WebJun 4, 2024 · Ubiquitin is a small (8.6 kDa) 76-residue regulatory protein which is found ‘ubiquitously’ in the cytoplasm and nucleus of eukaryotic cells and is a post-translational … can a uti cause headache

SUMO conjugation in plants SpringerLink

WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … WebApr 13, 2024 · Tumor cells are known to produce high amounts of intracellular lipids, leading to increased levels of fatty acids, cholesterol and membrane phospholipids. Death domain-associated protein (DAXX) is a small ubiquitin-related modifier (SUMO)-binding protein that plays a role in transcription regulation by interacting with transcription factors such as … fish in a small tankWebOct 1, 2024 · Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates multiple biological processes, including cell division, DNA … can a uti cause breakthrough bleeding

"WebMar 21, 2024 · SUMO2 (Small Ubiquitin Like Modifier 2) is a Protein Coding gene. Diseases associated with SUMO2 include Phlyctenulosis . Among its related pathways are Transport of the SLBP independent Mature mRNA and Homology Directed Repair . Gene Ontology (GO) annotations related to this gene include RNA binding and SUMO transferase activity . " - Small ubiquitin-related modifier 2

Small ubiquitin-related modifier 2

Concepts in sumoylation: a decade on - Nature

WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebSmall ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm. [ 1] [ 2] Immunogen human SUMO3 fusion protein Application Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and …

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WebOverview Product name Anti-Sumo 2 + Sumo 3 antibody See all Sumo 2 + Sumo 3 primary antibodies Description Rabbit polyclonal to Sumo 2 + Sumo 3 Host species Rabbit Specificity Recognises 2 bands representing Sumo 2 and Sumo 3 at 15 and 18kDa in Hela Nuclear extract by Western blotting. Tested applications WebNov 26, 2024 · Small ubiquitin-related modifiers (SUMOs) are a group of proteins known to greatly influence various cellular biological processes, 4 such as the cell cycle, signal …

WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase ... SUMO protease but functions on another small ubiquitin-re-latedproteinknownasNedd8(6,7).Thedefiningcharacteristic ... SUMO, small ubiquitin-like modifier; AFC, 7-amino-4-trifluoromethyl coumarin; DUB, de-ubiquitinating enzyme; WebSmall ubiquitin-related modifier (SUMO) 3The abbreviations used are: SUMO small ubiquitin-like modifier AFC 7-amino-4-trifluoromethyl coumarin DUB de-ubiquitinating enzyme SENP Sentrin-specific protease DTT dithiothreitol Ni-NTA nickel-nitrilotriacetic acid PIPES 1,4-piperazinediethanesulfonic acid MES 4-morpholineethanesulfonic acid CHES

UniProt P61956 · SUMO2_HUMAN Protein Small ubiquitin-related modifier 2 Gene SUMO2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 95 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST … See more This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. 1. Name1 2. See … See more WebMar 15, 2012 · SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the …

WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ...

fish in assawoman bayWebSep 23, 2004 · Covalent attachment of small proteins to substrates can regulate protein activity in eukaryotes. SUMO, the s mall u biquitin-related mo difier, can be covalently linked to a broad spectrum of substrates. An understanding of … fish in asiaWebFeb 11, 2011 · Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely … fish in a tank crosswordWebOct 12, 2015 · The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit … fish in aspicWebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO … fish in astronaut helmetIn molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional re… can a uti cause headache and nauseaWebFeb 22, 2005 · Importantly, Sp100 and PML are both covalently linked to small ubiquitin-related modifiers (SUMOs). Therefore, we investigated whether SUMO proteins are independent autoantigens in PBC and studied 99 PBC sera samples for reactivity against NDs, PML, and Sp100, as well as against SUMO-2 and SUMO-1 recombinant proteins. can a uti cause green discharge