WebOct 12, 2024 · nausea. abdominal pain. diarrhea. The two most serious side effects are liver failure and skeletal muscle damage. These are rare. Specifically, statins may lead to muscle damage in 1 in 10,000 ... WebAug 31, 2024 · Based on the long-term benefits calculations by Pencina and colleagues, 9 high-intensity statin use could prevent 51% to 71% of premature ASCVD events among patients age 30 to 39 years when treated for 30 years, which amounts to almost 1.4 million events in the United States. 9 This is an impressive statistic that requires careful …
High-Dose Statin Therapy in Patients With Stable …
WebMar 22, 2024 · Statin therapy is widely used for both the secondary and primary prevention of atherosclerotic cardiovascular disease. However, the randomized trials that have provided evidence of benefit have included few patients with heart failure (HF) [ 1,2 ]. However, two major randomized trials, CORONA and GISSI-HF, have directly addressed this issue in ... WebAtherosclerosis arises when fat, cholesterol, and other substances accumulate along artery walls and form a sticky buildup known as plaque. Left untreated, atherosclerosis can lead to atherosclerotic cardiovascular disease (ASCVD), which includes coronary heart disease, stroke, and peripheral arterial disease. charley\u0027s thai hawaii
Coronary artery disease (CAD): Causes, diagnosis and treatment
WebJul 15, 2024 · The investigators concluded that the risk of MI and all-cause mortality in patients without obstructive CAD is directly associated with the CAD burden. Statin … WebThis dichotomous threshold for low LDL was chosen because of the high frequency of LDL <2.0 mmol/L in statin-treated CAD patients 33 and data suggesting that cognition/brain functioning is theoretically most adversely affected when LDL serum concentrations are <1.5 mmol/L. 1, 34. The secondary exposure variable was high-dose versus low-dose ... WebNov 15, 2012 · In patients aged ≥80 years without previous coronary artery disease, peripheral vascular disease, or cerebrovascular disease, no evidence has shown a benefit from statin therapy. We examined the prevalence of statin use in patients aged ≥80 years for the indication of primary prevention. hart county scholarship alliance